From Metabolic Networks to Minimal Dynamic Bioreaction Models
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چکیده
The paper deals with the design of minimal dynamic bioreaction models in the situation where (a) the model is based on the knowledge of a detailed underlying metabolic network, (b) measurements of extra-cellular species in the reactor are the only available measurements. A brief but rigorous presentation of the theory is first given. Then the approach is illustrated with the example of chinese hamster ovary cells cultivated in stirred flasks. Copyright c ©2007 IFAC
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تاریخ انتشار 2007